Michael Chan
Bio
Professor Michael Chan received his PhD degree in Medical Science from the Chinese University of Hong Kong, followed by the post-doctoral fellowships in infectious diseases at The University of Hong Kong since 2004. Professor Chan's main research interests are the virus-host interaction and pathogenesis of influenza virus and coronavirus. Major focuses of his work are: (1) Risk assessment for tropism, replication and pathogenesis of influenza virus and coronavirus using ex vivo explants and organoids (2) Mechanism of lung injury upon severe influenza virus and coronavirus infection (3) Human nasal/nasopharyngeal, airway and alveolar organoids, personalized diseases and immune organoids development and risk assessment for emerging respiratory viruses (4) Role of human distal airway stem cells in respiratory epithelium regeneration upon virus infection. (5) Role of mesenchymal stromal cells and exosomes/microvesicles in reverse influenza H5N1 associated acute lung injury (6) Novel therapeutic options for severe human influenza virus and coronavirus infection. Professor Chan is ranked by Essential Science Indicator (ISI) as a "top 1% most-cited international scientist" in the world since 2009. He has published over 85 manuscripts; many of them are in high impact journals including Lancet Respiratory Medicine, Nature, Nature Medicine, Nature Microbiology, PNAS, etc. Professor Chan has played a number of scientific advisory roles for international organizations, as member of the Reference Laboratories of the WHO CoronaVirus Network (CoViNet), and WHO TIPRA consultation panel to provide risk assessment data on emerging influenza virus. Professor Chan has been worked as the visiting scientists in the Harvard Stem Cell Institute, Harvard Medical School and the Cardiovascular Research Institute, University of California, San Francisco. Professor Chan has received research funding as a Principal Investigator from various Hong Kong and oversea research organizations, including NIAID-CEIRR, NIH (USA), Theme-based Research Scheme, Area of Excellence Scheme and GRF (RGC, Hong Kong), ITF and Health@InnoHK (ITC, Hong Kong SAR), HMRF (Hong Kong SAR) with funding over HK$108 million. In knowledge exchange, Professor Chan has been coordinating the "Little Dr Flu" programme since 2013, which has successfully promoted the awareness of emerging respiratory virus infection and biomedical research and education among primary and secondary school students in Hong Kong.
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